Four fire crews from Aston, Maltby, Rotherham and Birley Moor stations were called to a sem-detached house on fire during the early hours of Saturday morning on Eastern Close in Dinnington, Rotherham.
Firefighters wearing breathing apparatus searched the property for occupants but no-one was inside.
Crews used main jets to tackle the fire.
An investigation is underway to determine the cause of the fire.